Postdoctoral Research Fellow or Research Associate – Cancer Epigenetics (2 Posts)
The Ontario Cancer Institute (OCI) at Princess Margaret Hospital - a teaching hospital of the University of Toronto - ranks in the top 5 cancer research centers in the world. Its research activities are concentrated on epigenomics, cancer immunotherapy, cancer stem cells, image-guided therapeutics, patient survivorship, and personalized medicine. The University of Toronto and its affiliated hospital research institutes comprise one of the largest and most productive centers of biomedical research in North America while the City of Toronto is ranked fourth in the Economist’s list of World’s Most Liveable Cities, and second in PriceWaterhouseCooper’s Cities of Opportunity in 2011.
For more information about the institute: http://www.uhntrainees.ca/
Computational Biology
A bioinformatics Postdoctoral Fellow or Research Associate position is available immediately within the group of Daniel D. De Carvalho, Ph.D. Our lab focuses on understanding the mechanisms driving cancer-specific epigenetic alterations, with the ultimate goal of allowing target-specific epigenetic interventions. To achieve this goal, we perform functional genomic screening, combined with systems biology and a variety of genome-wide profiling of epigenetic modifications, using next-generation sequencing (NGS) and microarray technologies. We are specifically seeking individuals with strong computational, bioinformatics, and/or statistical backgrounds to be involved in NGS data analysis. Applicants must be highly motivated and able to communicate effectively in English.
Molecular Biology/Immunology
A postdoctoral Fellow or Research Associate position is available immediately within the group of Daniel D. De Carvalho, Ph.D. We are seeking individuals with a solid background in Molecular biology and/or immunology to lead the investigation into the mechanisms of epigenetic therapy as a primer for cancer immune-therapy. Applicants must be familiar with some of the following techniques: quantitative qPCR, mammalian cell culture, cloning, RNAi, shRNA library, ChIP, western blot, flow cytometry and luminex. Applicants must be highly motivated and able to communicate effectively in English.
For more information about our work, prospective applicants are encouraged to refer to the following papers: Cancer Cell. 2012 May 25;21(5):655-67 (PMID: 22624715);
Cell. 2011 Dec 9;147(6):1283-94 (PMID: 22153073);
PNAS. 2011 Aug 30;108(35):14497-502 (PMID: 21844352);
PLoS Genet. 2011 Feb 3;7(2):e1001286 (PMID: 21304883);
Nat Biotechnol. 2010 Oct 13;28(10):1069- 1078 (PMID: 20944599); Oncogene. 2011 Jan 13;30(2):223-33 (PMID: 20838376).
Please send your curriculum vitae and the contact information for 3 references to Daniel D. De Carvalho, Ph.D. (ddecarv@uhnresearch.ca).
The Ontario Cancer Institute (OCI) at Princess Margaret Hospital - a teaching hospital of the University of Toronto - ranks in the top 5 cancer research centers in the world. Its research activities are concentrated on epigenomics, cancer immunotherapy, cancer stem cells, image-guided therapeutics, patient survivorship, and personalized medicine. The University of Toronto and its affiliated hospital research institutes comprise one of the largest and most productive centers of biomedical research in North America while the City of Toronto is ranked fourth in the Economist’s list of World’s Most Liveable Cities, and second in PriceWaterhouseCooper’s Cities of Opportunity in 2011.
For more information about the institute: http://www.uhntrainees.ca/
Computational Biology
A bioinformatics Postdoctoral Fellow or Research Associate position is available immediately within the group of Daniel D. De Carvalho, Ph.D. Our lab focuses on understanding the mechanisms driving cancer-specific epigenetic alterations, with the ultimate goal of allowing target-specific epigenetic interventions. To achieve this goal, we perform functional genomic screening, combined with systems biology and a variety of genome-wide profiling of epigenetic modifications, using next-generation sequencing (NGS) and microarray technologies. We are specifically seeking individuals with strong computational, bioinformatics, and/or statistical backgrounds to be involved in NGS data analysis. Applicants must be highly motivated and able to communicate effectively in English.
Molecular Biology/Immunology
A postdoctoral Fellow or Research Associate position is available immediately within the group of Daniel D. De Carvalho, Ph.D. We are seeking individuals with a solid background in Molecular biology and/or immunology to lead the investigation into the mechanisms of epigenetic therapy as a primer for cancer immune-therapy. Applicants must be familiar with some of the following techniques: quantitative qPCR, mammalian cell culture, cloning, RNAi, shRNA library, ChIP, western blot, flow cytometry and luminex. Applicants must be highly motivated and able to communicate effectively in English.
For more information about our work, prospective applicants are encouraged to refer to the following papers: Cancer Cell. 2012 May 25;21(5):655-67 (PMID: 22624715);
Cell. 2011 Dec 9;147(6):1283-94 (PMID: 22153073);
PNAS. 2011 Aug 30;108(35):14497-502 (PMID: 21844352);
PLoS Genet. 2011 Feb 3;7(2):e1001286 (PMID: 21304883);
Nat Biotechnol. 2010 Oct 13;28(10):1069- 1078 (PMID: 20944599); Oncogene. 2011 Jan 13;30(2):223-33 (PMID: 20838376).
Please send your curriculum vitae and the contact information for 3 references to Daniel D. De Carvalho, Ph.D. (ddecarv@uhnresearch.ca).
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