The Transplant Research Center (Harvard Medical School, Brigham and Women's
Hospital) is committed to the development of novel agents to promote immune
regulation in transplantation and to identify biomarkers for the earlier
diagnosis of allograft rejection/injury.
Our research center integrates both basic science and translational aspects
of transplantation. Experimental mouse models of transplantation (heart,
kidney, skin and bone marrow), nanotechnology for drug delivery, cellular
therapy, and manipulation of T/B cell response via biological and small
molecules are some of our basic science expertise. In the translational arena, our center is a
core immunological lab for the CTOT trials and we have currently three
ongoing large translational clinical trials of transplantation, in which we are
attempting to identify markers of rejection/injury, characterize the
allo-antibody response in patients with chronic rejection and investigate
signatures for over- or under-immunosuppression in kidney transplant
recipients.
We have access to
technologies such as Mass Cytometry, Metabolomic profiling and in vivo confocal microscopy.
We
actively recruit postdoctoral fellows for positions in the lab (graduate
students are considered in special cases). Talented and motivated fellows are sought with a background
in science, medicine or research. A
two-year commitment is required, US citizens and permanent US residents are
encouraged to apply but priority is also given to fellows from abroad who are
self-funded. Prior experience with immunology research is important.
If
you would like to be considered for a position, please contact us and provide
an updated C.V. and a short personal statement (1-2 paragraphs). References will be required.
**************************************************
Leonardo V. Riella, MD, PhD, FASN
Assistant Professor of Medicine,
Harvard Medical School
Associate Physician, Brigham and
Women's Hospital
Associate Director of Kidney
Transplantation
lriella@rics.bwh.harvard.edu
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