segunda-feira, 31 de dezembro de 2012

Paper de 2012 na Imunologia IV

Sugestão da blogueira Andréa Teixeira


An integrated encyclopedia of DNA elements in the human genome. The ENCODE Project Consortium et al., Nature. 2012 Sep 6;489(7414):57-74. doi: 10.1038/nature11247.





2 comentários:

  1. Com certeza as publicações do ENCODE estão entre as mais importantes esse ano.

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  2. The Encyclopedia of DNA Elements (ENCODE) project has systematically mapped regions of transcription, transcription factor association, chromatin structure and histone modification. These data enabled us to assign biochemical functions for 80% of the genome, in particular outside of the well-studied protein-coding regions. Many discovered candidate regulatory elements are physically associated with one another and with expressed genes, providing new insights into the mechanisms of gene regulation.bupropion duloxetine flunitrazepam sucralfate oxytocin hyoscyamine loperamide atorvastatin metformin cabergoline cilostazol buprenorphine cefalexin clopidogrel moxifloxacin cefdinir clindamycin itraconazole penicillin benzathine dutasteride carbamazepine prazosin triamcinolone felodipine captopril sotalol valsartan capsaicin megestrol nitroglycerin

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