sexta-feira, 23 de dezembro de 2011

Capa da Immunity - Dez/2012

Colegas,


foi com grata satisfação que recebemos a notícia de que o grupo liderado pelo Dr. Alan Sher, com participação do nosso colaborador Bruno Bezerril, publicou um excelente manuscrito na edição deste mês da Immunity, com direito a capa da revista e tudo mais.

Parabéns a todos os envolvidos com o trabalho!


Link para o artigo: AQUI



"On the cover: Interleukin-1β (IL-1β) is known to important for protection during Mycobacterium tuberculosis infection. Mayer-Barber et al. (pages 1023–1034) show an additional critical protective role for IL-1α and identify two myeloid subsets as the source of these important inflammatory cytokines in the infected lung. On the cover is an artistic depiction of the heterogeneous nature of these two pulmonary DC-macrophage subsets, as well as interactions between antigen-presenting cells and T cells in the lungs of M. tuberculosis (brown)-infected mice. Each colored cell represents a functionally distinct subset of DCs or monocytes-macrophages and, in case of the smaller round cells, different CD4+ T helper cell subsets. The myeloid subsets are multifunctional and, in addition to IL-1α and IL-1β, produce a specific set of cytokines (represented by small, round particles), which in turn are regulated by interferons from infected cells and T lymphocytes. Cover art by Katrin Mayer-Barber."


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